ABSTRACT. - The Climactic Premises of Organizing the Agricultural Area of Giurgeu Depression. The Giurgeu Basin is one of the coldest microregions both of the country and Middle – East Europe. Its ecological infrastructure follows the specific climatic particularities, and it presents a characteristic flora, fauna and soils. Among the natural conditions required by agriculture, the climate is of decisive importance. The agro-structure of this microregion has never been too varied. In the past 50 years, however, it has become more restricted, and the exchange of agricultural products has increasingly become more and more deficitary. Agricultural production must be laid on new bases. In the process, of a great importance is defense against risk factors, and also an ever – increasing put into value of the southern and south – western slopes, which show a more favorable climate. Thinking in microregional terms, we cannot have in view a market – centered agriculture. The only way to proceed is to create a multi – functional agriculture, with a deep ecological basis, which is able to follow the specific ecological infrastructure of the basin.